Psychopharmacology
Convergence-based reasoning around MAOIs, serotonin toxicity, and the difference between what works on paper and what works in people.
qualia + pharmacology
Alexander Duncan Guitar
Studying what it feels like to be alive — through brain chemistry, murder pop, and a 3,000-person community that actually gives a shit.
Psychopharmacology researcher, NAMI co-facilitator, and the artist behind Doopliss. Qualiacology is where the serious work, the strange songs, and the people trying to get it right finally live under one roof.
qualiacology
QUALIA
The chemistry of subjective experience, traced through mechanism, music, and real human mess.
Doopliss
Bright melodies, dark subtext, and pop songs that smile sweetly right before they bite.
Discord
We study medication, help people, and chill with friends. 3,000+ members strong.
This Helped Someone
A puzzle-piece framework for finding what actually fits in psychiatric medicine — without pretending there’s one magic answer.
Community
The Psychopharmacology Server
We study medication, help people, and chill with friends. 3,000+ members exploring the world of psychopharmacology together — no gatekeeping, no judgment, just real talk.
At the heart of our community, we explore the intricacies of medications — delving deep into how they actually work in the brain and in real life. We commit to supporting each other through the hard parts. And we cherish the friendships that form when people stop pretending and start being honest about what they’re going through.
Hard questions are welcome — interactions, side effects, MAOI confusion, tapering, serotonin toxicity fears, and the general mess of trying to make good decisions when the internet is full of confident bullshit. The vibe is serious without being sterile, and friendly without being fake.
Study medication
Help people
Chill with friends
Game
No Moon
A luminous browser roguelike about strange little Passengers descending through sealed rooms beneath a missing sky. Dodge ritual bullet patterns, graft relics into your Hull, uncover side routes, and follow the Bellways downward until the world starts admitting what it has been hiding.
Playable now • browser arcade descent
No Moon
Fight through beautiful little death-rooms, crack open boss ceremonies, collect glass-star splinters, discover hidden reliquaries, and decide whether to keep descending or step through the strange side doors the dungeon pretends it did not build.
01
Fast readable combat
Compact twin-stick chambers built for dodge, fire, read, survive — with less mid-fight prose and clearer danger.
02
Builds that mutate
Grafts, active relics, boss trophies, and Passenger quirks turn each descent into a volatile little machine.
03
Secrets with teeth
Hidden reliquaries, strange side doors, the Ferry Dock, and route discoveries that feel found, not advertised.
04
Progress with memory
The Field Guide tracks grafts, boss cards, and unlocked Passengers without turning the game into a chore list.
Music
Doopliss
Bright, catchy, upbeat melodies with psychologically dark, emotionally raw lyrics — murder pop on purpose. The hooks invite you in. The subtext quietly locks the door behind you.
Doopliss lives in that deliciously wrong sweet spot between neon-pop seduction and emotional sabotage. It’s playful, glossy, a little dangerous, and never interested in pretending the dark stuff only sounds dark.
Immortalized
The one where redemption was never on the table and the songs are the receipt. He doesn’t repent — he gets remembered. Lacquered into permanence by the same glossy hooks that should have buried him.
Doopliss
Hate Fuck Hotline
dial tone pop
Hate Fuck Hotline
The newest dispatch from the Doopliss emergency broadcast system. Dial in, regret it later, and don’t pretend you weren’t warned by the title.
Listen on Suno
Doopliss
Pretty Guilty
12 songs
Pretty Guilty
The one where the verdict was never in question but the sentencing keeps getting delayed. Gorgeous on the surface, rotting underneath, and completely okay with it.
Listen on SunoBite Marks & Bubblegum
The one that smiles with perfect lipstick while the floor drops out underneath you. Glossy hooks, bruised undertones, and the exact second attraction starts looking like self-destruction.
Death Threats & Makeup Sex
The big one. Twenty-eight tracks of the entire toxic cycle on repeat — the fight, the fuck, the apology, the amnesia, the relapse. The album that proves love and destruction share a zip code.
Cherry Lipstick (And Other Red Flags)
A glittering field guide to attraction, denial, and knowing better about five seconds too late. Romantic comedy energy with a switchblade hidden somewhere in the purse.
The Book
This Helped Someone
A framework for finding what works in psychiatric medicine — without reducing people to a checklist or pretending one person’s answer is everybody’s answer.
This Helped Someone
A Framework for Finding What Works in Psychiatric Medicine
Psychiatric treatment can feel like dumping a thousand mismatched puzzle pieces onto a table and being told the picture should already make sense. This book offers a practical way to sort the pieces — mechanism, history, tradeoffs, side effects, context, and lived experience — so people can stop treating themselves like failed experiments and start recognizing what actually fits.
It’s not a promise of one magical answer. It’s a clearer way to think when the stakes are personal, the information is messy, and the usual advice feels either too vague or too confident.
Sort the pieces
Find the difference between random noise, real signal, and the variables that actually matter.
Think in tradeoffs
Medication choices are rarely about perfection; they’re about fit, priorities, and tolerable compromises.
Keep the human in view
Mechanism matters, but so do history, values, trauma, routine, and the weird chemistry of real life.
About
Researcher. Artist. The guy running the Discord.
Different fronts of the same obsession: understanding brain chemistry, figuring out what actually works, and saying something real about what it feels like to be here.
Alexander Duncan Guitar
behavioral neuroscience / psychopharmacology / Doopliss / community
I come out of behavioral neuroscience, but the center of my work has always been much messier and more human than a clean academic bio makes it sound. I focus especially on MAOIs, serotonin toxicity, and the places where bad assumptions can do real damage and careful thinking actually matters.
Ken Gillman’s work has been a major influence on how I think about psychiatric medication: follow the evidence, stay honest about uncertainty, and don’t confuse confidence with accuracy. My framework is about convergence — truth in psychiatry doesn’t come from any single source, it emerges when multiple independent lines of evidence point the same direction.
Mechanism explains what should happen. Trials show what can happen under controlled conditions. Experts recognize patterns. Prescribers see what survives real life. Patients reveal whether the result is actually livable. The truth is the fit.
Alongside that, I co-facilitate NAMI support groups, run a 3,000+ member psychopharmacology Discord community, and make music as Doopliss — because for me, science, art, and community are all the same project from different angles.
I’m interested in what helps, what harms, and how people navigate the weird emotional weather of being alive without getting flattened by jargon, panic, or fake expertise. I give a shit about getting this right.
“Science for the chemistry. Music for the feeling. Community for the parts nobody should do alone.”
Behavioral neuroscience
MAOIs / serotonin toxicity
Ken Gillman influence
NAMI facilitation
Doopliss
Connect
Find the right door.
Best way to reach me: email, Instagram DMs, or jump into the Discord. Everything else is here if you want the full trail of evidence, noise, hooks, and neon.
If you’re here for the psychopharmacology work, the Discord is the fastest way into the community. If you’re here for the music, Suno and TikTok are where the Doopliss side gets loud. If you just want to say hi like a normal person, shoot me an email or hit my Instagram DMs.
Qualiacology is meant to be a central hub, not a maze. Pick the door that matches the version of me you were looking for.